Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep1117 | Female Reproduction | ECE2017

Pharmacokinetics and bioavailability of non-polar phytocomponents of Aloe vera gel and their role as an endocrine modulator in letrozole induced PCOS rat model

Dey Arpi , Vasoya Shweta , Nampoothiri Laxmipriya

Background and aim: Polycystic ovary syndrome (PCOS), the most common endocrine disorder in women of reproductive age with an estimated prevalence of 5–10%, is one of the most common causes of female infertility. The therapeutic options for PCOS are limited. Thereby, traditional knowledge of Ayurveda has been exploited to identify an herbal therapeutic target for PCOS. Pharmacokinetic (PK) studies on bioactive constituents of herbal drugs provide valuable information on b...

ea0037ep140 | Reproduction, endocrine disruptors and signalling | ECE2015

Implication of non polar phytocomponents of aloe vera gel in management of polycystic ovarian syndrome

Nampoothiri Laxmipriya , Maharjan Radha , Dey Arpi

Background: Aloe vera gel has been proven to have hypoglycaemic, hypolipidemic, and steroid enzyme regulating properties. These are of clinical significance in reproductive pathology namely polycystic ovary syndrome (PCOS). Preliminary, ‘in-vitro’ studies suggested that non-polar component is responsible for the steroid enzyme modulating effect. This study investigates the role of non polar phytocomponent’s of aloe vera gel, which could be responsible i...